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Article

Inactive type II and type I receptors for TGF beta are dominant inhibitors of TGF beta-dependent transcription.

The Journal of biological chemistry - 7 Apr 1995

Brand T, Schneider M D

Abstract excerpt

Although transforming growth factor-beta (TGF beta) is implicated in differentiation and disease, proof of in vivo function requires specific inhibitors of the TGF beta cascade. TGF beta binds a family of type I and type II receptors (T beta RI, T beta RII), containing a cytoplasmic serine/threonine kinase domain. We previously reported that kinase-deficient T beta RII (delta kT beta RII) blocks TGF...

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PMID: 7713935
DOI: 10.1074/jbc.270.14.8274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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