Article
ZBP-89 represses vimentin gene transcription by interacting with the transcriptional activator, Sp1.
Nucleic acids research - 1 Jun 2003
Zhang Xueping, Diab Iman H, Zehner Zendra E
Abstract excerpt
Vimentin, a member of the intermediate filament protein family, is regulated both developmentally and tissue specifically. It is also a marker of the metastatic potential of many tumor cells. Pre viously, the human vimentin promoter has been shown to contain multiple elements for the binding of both positive- and negative-acting regulatory factors. Transient transfection analysis of various vimentin 5'-end...
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