Article
Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein.
The EMBO journal - 24 Nov 2004
Gagrica Sladjana, Hauser Stefanie, Kolfschoten Ingrid, Osterloh Lisa, Agami Reuven, Gaubatz Stefan
Abstract excerpt
Genetic studies in Caenorhabditis elegans identified lin-9 to function together with the retinoblastoma homologue lin-35 in vulva differentiation. We have now identified a human homologue of Lin-9 (hLin-9) and provide evidence about its function in the mammalian pRB pathway. hLin-9 binds to pRB a...
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