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Article

Polymorphism of the ERalpha and CYP1B1 genes in endometrial cancer in a Polish subpopulation.

The journal of obstetrics and gynaecology research - 1 Apr 2010

Sliwinski Tomasz, Sitarek Przemyslaw, Stetkiewicz Tomasz, Sobczuk Anna, Blasiak Janusz

Abstract excerpt

AIM: Metabolic activation of estrogens may play a role in endometrial carcinogenesis; and polymorphism of the genes (whose product is involved in this process) may be associated with the modulation of the risk of endometrial cancer. CYP1B1 plays a major role in the metabolism of estrogens, which must firstly bind their receptors, estrogen receptor alpha (ERalpha) or ER beta. In the present study we investigated...

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Source

Identifiers

PMID: 20492382
DOI: 10.1111/j.1447-0756.2009.01143.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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