Article
Regulation of the phenotype of ovarian somatic cells by estrogen.
Molecular and cellular endocrinology - 28 Apr 2003
Britt Kara L, Findlay Jock K
Abstract excerpt
The pathway of mammalian sex determination, and subsequent differentiation of the gonads is under the control of the sex-determining gene, Sry, on the Y chromosome. The presence of Sry leads to the formation of a testis with its complement of Sertoli and Leydig somatic cells. In the absence of Sry, an ovary develops with granulosa and theca cells. Ovarian development is said to initiate in the XX gonad as a...
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