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Article

Estrogen Is Not Directly Required for Oocyte Developmental Competence1

1 May 2004

Abstract excerpt

Oocyte maturation and ovulation require a coordinated interaction between gonadotrophs, steroid hormones, and growth factors. The extent to which estrogen is required in this process, however, remains unclear. To better understand the role of estrogen in maintaining developmental competence of mammalian oocytes, we studied the Aromatase knockout (ArKO) mouse, which has been genetically engineered to be incapable...

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Share to Estrogen and related hormone effects
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PMID: 14695903
DOI: 10.1095/biolreprod.103.022111

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