Article
Contrasting phenotypes in reproductive tissues of female estrogen receptor null mice.
Annals of the New York Academy of Sciences - 1 Dec 2001
Couse J F, Korach K S
Abstract excerpt
The estrogen receptor (ER) exists in two known forms, ERalpha and ERbeta, and acts as a ligand-inducible transcription factor to fulfill critical roles in reproductive physiology. Although in vitro studies suggest the ERs may play redundant roles, a dissimilar tissue distribution indicates otherwise. Therefore, to gain insight into the role of each ER form, individual lines of mice lacking each respective...
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