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Article

Estrogen-Dependent Gene Expression in the Mouse Ovary

9 Feb 2011

Abstract excerpt

Estrogen (E) plays a pivotal role in regulating the female reproductive system, particularly the ovary. However, the number and type of ovarian genes influenced by estrogen remain to be fully elucidated. In this study, we have utilized wild-type (WT) and aromatase knockout (ArKO; estrogen free) mouse ovaries as an in vivo model to profile estrogen dependent genes. RNA from each individual ovary (n = 3) was...

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PMID: 21347412
DOI: 10.1371/journal.pone.0014672

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