Article
Mutational analysis of the serotonergic system: recent findings using knockout mice.
Current drug targets. CNS and neurological disorders - 1 Oct 2002
Gingrich Jay A
Abstract excerpt
Serotonin modulates numerous processes in the central nervous system related to anxiety and fear, mood, aggression, sleep, ingestive behaviors, reward systems, and psychosis. Serotonergic dysfunction has been implicated in several neuropsychiatric conditions but efforts to develop more specific pharmacological agents have been hampered by the complexity of this system at the receptor level. There are at least 14...
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