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Article

TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-kappa B through TNF receptor-associated factors.

Biochemical and biophysical research communications - 13 Jun 2003

Han Songyi, Yoon Kwiyeom, Lee Kyunghye, Kim Kyunghee, Jang Hyunduk, Lee Na Kyung, Hwang Kichul, Young Lee Soo

Abstract excerpt

TNF-related weak inducer of apoptosis (TWEAK) is a member of the TNF ligand family that induces angiogenesis in vivo. The TWEAK receptor (TweakR) is a recently identified member of the TNF receptor (TNFR) superfamily and is expressed on smooth muscle cells (SMCs) and endothelial cells (ECs). In this report we identify the TNF receptor-associated factor (TRAF) family of signal transducers as important components...

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Source

Identifiers

PMID: 12767899
DOI: 10.1016/s0006-291x(03)00852-0

Genes

TNF
TRAF2
TRAF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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