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Article

TWEAK/Fn14 axis is an important player in fibrosis

30 Sept 2020

Abstract excerpt

Fibrosis is a common pathological condition associated with abnormal repair after tissue injury. However, the etiology and molecular mechanisms of fibrosis are still not well-understood. Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) belongs to the TNF superfamily and acts by binding to its receptor, fibroblast growth factor-inducible 14 (Fn14), thereby activating a variety of intracellular...

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PMID: 33000480
DOI: 10.1002/jcp.30089

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