Article
Characterization of the interaction of wheat HMGa with linear and four-way junction DNAs.
Biochemistry - 3 Jun 2003
Zhang Wensheng, Wu Qiang, Pwee Keng-Hock, Jois Seetharama D S, Kini R Manjunatha
Abstract excerpt
Wheat HMGa protein is a typical member of the plant HMGA family. It has four AT hooks and a histone H1-like region. A panel of deletion mutants of HMGa was generated to study the role of different regions of HMGa in its binding to 4H (a synthetic DNA that mimics the in vivo structure of intermediates of homologous recombination and DNA repair) and linear DNAs. Although the histone H1-like region of HMGa does not...
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