Article
[Molecular aetiology of nodular goitre -- consequences for therapy?].
Zentralblatt fur Chirurgie - 1 Oct 2004
Brauer V F, Paschke R
Abstract excerpt
Up to 15 % of the adult German population display an enlarged thyroid gland and up to 30 % present thyroid nodules. Iodine deficiency is the most important factor in the etiology of nodular goiter. Insulin-like growth factor-I is overexpressed in thyroids in severely iodine deficient areas. There is evidence that iodolactones are mediators of thyroid hormone autoregulation. However familial and twin studies...
Topics
- Genetic Linkage
- Genetic Markers
- Genotype
- Goiter, Nodular
- Humans
- Iodine
- Primary Prevention
- Recurrence
- Risk Factors
- Thyroidectomy
