Article
The TSH receptor and its role in thyroid disease.
Cellular and molecular life sciences : CMLS - 1 Aug 2001
Kopp P
Abstract excerpt
The thyrotropin (TSH) receptor plays a preeminent role in thyroid physiology and disease. TSH, acting through the TSH receptor, is the major stimulator of thyroid cell growth, differentiation and function. In Graves' disease, the TSH receptor is the target of stimulating antibodies that cause hyperthyroidism. Although still a topic of debate, the TSH receptor has been implicated in the pathogenesis of the...
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