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Article

Dedifferentiation and Proliferation of Surviving Epithelial Cells in Acute Renal Failure

1 Jun 2003

Abstract excerpt

In contrast to the heart or brain, the kidney can completely recover from an ischemic or toxic insult that results in cell death. During recovery from ischemia/reperfusion injury, surviving tubular epithelial cells dedifferentiate and proliferate, eventually replacing the irreversibly injured tubular epithelial cells and restoring tubular integrity. Repair of the kidney parallels kidney organogenesis in the high...

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PMID: 12761240
DOI: 10.1097/01.asn.0000067652.51441.21

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