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Article

Epithelial Cell Cycle Behaviour in the Injured Kidney

13 Jul 2018

Abstract excerpt

Acute kidney injury (AKI), commonly caused by ischemia-reperfusion injury, has far-reaching health consequences. Despite the significant regenerative capacity of proximal tubular epithelium cells (PTCs), repair frequently fails, leading to the development of chronic kidney disease (CKD). In the last decade, it has been repeatedly demonstrated that dysregulation of the cell cycle can cause injured kidneys to...

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PMID: 30011818
DOI: 10.3390/ijms19072038

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