Article
Catalases of Aspergillus fumigatus.
Infection and immunity - 1 Jun 2003
Paris Sophie, Wysong Deborah, Debeaupuis Jean-Paul, Shibuya Kazutoshi, Philippe Bruno, Diamond Richard D, Latgé Jean-Paul
Abstract excerpt
Upon infection of a host, the pathogenic fungus Aspergillus fumigatus is attacked by the reactive oxygen species produced by phagocytic cells. Detoxification of hydrogen peroxide by catalases was proposed as a way to overcome this host response. A. fumigatus produces three active catalases; one is produced by conidia, and two are produced by mycelia. The mycelial catalase Cat1p was studied previously. Here we...
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