Article

Photoinactivation of catalase sensitizes <i>Candida albicans</i> and <i>Candida auris</i> to ROS-producing agents and immune cells

2021-08-31

Abstract excerpt

Nearly all organisms found in nature have evolved and developed their own specific strategies to cope with reactive oxygen species (ROS). Catalase, a heme-containing tetramer protein expressed in a broad range of aerobic fungi, has been utilized as an essential enzymatic ROS detoxifying mechanism, and shows remarkable efficiency in degrading hydrogen peroxide (H 2 O 2 ) for fungal cell survival and host invasion...

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Literature Corpus work: ed02f624-3efe-5339-a605-385009219698
DOI: 10.1101/2021.08.31.458449

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