Article
Cloning and disruption of the antigenic catalase gene of Aspergillus fumigatus.
Infection and immunity - 1 Nov 1997
Calera J A, Paris S, Monod M, Hamilton A J, Debeaupuis J P, Diaquin M, López-Medrano R, Leal F, Latgé J P
Abstract excerpt
Aspergillus fumigatus possesses two catalases (described as fast and slow on the basis of their electrophoretic mobility). The slow catalase has been recognized as a diagnostic antigen for aspergillosis in immunocompetent patients. The antigenic catalase has been purified. The enzyme is a tetrameric protein composed of 90-kDa subunits. The corresponding cat1 gene was cloned, and sequencing data show that the cat1...
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