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Article

Cloning and Sequencing of a <i>Candida albicans</i> Catalase Gene and Effects of Disruption of This Gene

1 May 1998

Abstract excerpt

Catalase plays a key role as an antioxidant, protecting aerobic organisms from the toxic effects of hydrogen peroxide, and in some cases has been postulated to be a virulence factor. To help elucidate the function of catalase in Candida albicans, a single C. albicans-derived catalase gene, designated CAT1, was isolated and cloned. Degenerate PCR primers based on highly conserved areas of other fungal catalase...

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Identifiers

PMID: 9573075
DOI: 10.1128/iai.66.5.1953-1961.1998

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