Article
Ambulatory blood pressure and left ventricular structure and function in relation to the G-protein beta3-subunit polymorphism C825T in White Europeans.
Journal of human hypertension - 1 May 2003
Olszanecka A, Kawecka-Jaszcz K, Kuznetsova T, Stolarz K, Brand E, Ryabikov A, Herrmann S-M, Nikitin Y, Staessen J A
Abstract excerpt
The 825T allele of the G-protein beta(3)-subunit is associated with increased intracellular signalling. Its association with hypertension is inconsistent. We, therefore, studied the C825T polymorphism in relation to ambulatory blood pressure as well as left ventricular structure and function in two European populations. We genotyped 248 parents and 318 offspring, enrolled in the European Project on Genes in...
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