Article
Relation of the G protein beta3-subunit polymorphism with left ventricle structure and function.
Hypertension (Dallas, Tex. : 1979) - 1 Aug 2002
Sedlácek Kamil, Fischer Marcus, Erdmann Jeanette, Hengstenberg Christian, Holmer Stephan, Kürzinger Susanne, Muscholl Michael, Luchner Andreas, Riegger Günter A, Hense Hans-Werner, Schunkert Heribert
Abstract excerpt
The G protein beta3-subunit C825T polymorphism results in a truncated splice variant protein that is associated with enhanced transmembrane signaling, increased proliferative activity, and arterial hypertension. The aim of the present study was to further investigate the association of this polymorphism with left ventricular (LV) structure and function. A total of 2052 individuals from a large-scale...
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