Article
Localization and characterization of the inhibitory Ca2+-binding site of Physarum polycephalum myosin II.
The Journal of biological chemistry - 25 Jul 2003
Farkas Laszlo, Malnasi-Csizmadia Andras, Nakamura Akio, Kohama Kazuhiro, Nyitray Laszlo
Abstract excerpt
A myosin II is thought to be the driving force of the fast cytoplasmic streaming in the plasmodium of Physarum polycephalum. This regulated myosin, unique among conventional myosins, is inhibited by direct Ca2+ binding. Here we report that Ca2+ binds to the first EF-hand of the essential light ch...
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