Kinetic studies of calcium binding to the regulatory site of troponin C from cardiac muscle.

doi:10.1074/jbc.271.2.688

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Article

Kinetic studies of calcium binding to the regulatory site of troponin C from cardiac muscle.

The Journal of biological chemistry - 12 Jan 1996

Dong W, Rosenfeld S S, Wang C K, Gordon A M, Cheung H C

Abstract excerpt

We have studied the kinetics of the structural transitions induced by calcium binding to the single, regulatory site of cardiac troponin C by measuring the rates of calcium-mediated fluorescence changes with a monocysteine mutant of the protein (C35S) specifically labeled at Cys-84 with the fluor...

Topics

Animals
Calcium
Calcium-Binding Proteins
Kinetics
Mutation
Myocardium
Protein Folding
Rats
Troponin
Troponin C

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