Article
Dual regulation by phospho‐OmpR of ssrA/B gene expression in Salmonella pathogenicity island 2
1 May 2003
Abstract excerpt
Expression of genes located on Salmonella pathogenicity island 2 (SPI-2) is required for systemic infection in mice. This region encodes a type III secretion system, secreted effectors and the two-component regulatory system SsrA/B (also referred to as SpiR), as well as additional uncharacterized genes. In the present work, we demonstrate that phospho-OmpR (OmpR-P) functions as an activator at the spiC-ssrA/B...
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