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Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine

16 Nov 2005

Abstract excerpt

Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that causes disease in mice that resembles human typhoid. Typhoid pathogenesis consists of distinct phases in the intestine and a subsequent systemic phase in which bacteria replicate in macrophages of the liver and spleen. The type III secretion system encoded by Salmonella pathogenicity island 2 (SPI-2) is a major virulence factor...

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PMID: 16304611
DOI: 10.1371/journal.ppat.0010032

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