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Article

A horizontally acquired transcription factor coordinates Salmonella adaptations to host microenvironments.

mBio - 23 Sept 2014

Brown Nat F, Rogers Lindsay D, Sanderson Kristy L, Gouw Joost W, Hartland Elizabeth L, Foster Leonard J

Abstract excerpt

UNLABELLED: The transcription factors HilA and SsrB activate expression of two type III secretion systems (T3SSs) and cognate effectors that reprogram host cell functions to benefit infecting Salmonella in the host. These transcription factors, the secretion systems, and the effectors are all encoded by horizontally acquired genes. Using quantitative proteomics, we quantified the abundance of 2,149 proteins from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25249283
DOI: 10.1128/mBio.01727-14
PMCID: PMC4173766

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