Article
A limited role for SsrA/B in persistent Salmonella Typhimurium infections in pigs.
Veterinary microbiology - 30 Apr 2008
Boyen Filip, Pasmans Frank, Van Immerseel Filip, Morgan Eirwen, Botteldoorn Nadine, Heyndrickx Marc, Volf Jiri, Favoreel Herman, Hernalsteens Jean-Pierre, Ducatelle Richard, Haesebrouck Freddy
Abstract excerpt
Virulence genes regulated by the SsrA/B system are indispensable for systemic disease in BALB/c mice. The role of this regulating system in the pathogenesis of Salmonella Typhimurium infections in pigs is not documented. In the present study, the interactions of Salmonella Typhimurium and an ssrA/B mutant were compared in vitro and in vivo. The ssrA/B mutant strain displayed decreased Salmonella Pathogenicity...
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