Article
ssrA (tmRNA) plays a role in Salmonella enterica serovar Typhimurium pathogenesis.
Journal of bacteriology - 1 Mar 2000
Julio S M, Heithoff D M, Mahan M J
Abstract excerpt
Escherichia coli ssrA encodes a small stable RNA molecule, tmRNA, that has many diverse functions, including tagging abnormal proteins for degradation, supporting phage growth, and modulating the activity of DNA binding proteins. Here we show that ssrA plays a role in Salmonella enterica serovar Typhimurium pathogenesis and in the expression of several genes known to be induced during infection. Moreover, the...
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