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Article

Quantitative trait loci modulate ventricular size in the mouse brain.

The Journal of comparative neurology - 30 Jun 2003

Zygourakis Corinna C, Rosen Glenn D

Abstract excerpt

Cerebral ventricular size in humans varies significantly. Abnormal enlargement of the ventricles has been associated with schizophrenia, and hydrocephalus can lead to serious cognitive and motor deficiencies in humans and animals. In this study, we mapped quantitative trait loci (QTLs) modulating cerebroventricular size in mice. We hypothesized that genes underlying hydrocephalus might also modulate normal...

Topics

Animals
Brain
Cerebral Ventricles
Chromosome Mapping
Chromosomes
Diagnostic Imaging
Genetic Markers
Genetic Variation
Lateral Ventricles
Mice
Mice, Inbred C57BL
Mice, Inbred Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Organ Size

Polymorphism, Genetic

Quantitative Trait Loci

Recombination, Genetic

Third Ventricle

Source

Identifiers

PMID: 12746874
DOI: 10.1002/cne.10697

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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