Article
The genetic control of neocortex volume and covariation with neocortical gene expression in mice.
BMC neuroscience - 9 May 2009
Gaglani Shiv M, Lu Lu, Williams Robert W, Rosen Glenn D
Abstract excerpt
BACKGROUND: The size of the cerebral cortex varies widely within human populations, and a large portion of this variance is modulated by genetic factors. The discovery and characterization of these genes and their variants can contribute to an understanding of individual differences in brain development, behavior, and disease susceptibility. Here we use unbiased stereological techniques to map quantitative trait...
Topics
- Animals
- Chromosome Mapping
- Functional Laterality
- Gene Expression Profiling
- Genetic Variation
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Inbred Strains
- Neocortex
- Organ Size