Article
Quantitative trait loci linked to thalamus and cortex gray matter volumes in BXD recombinant inbred mice.
Heredity - 1 Jul 2007
Dong H, Martin M V, Colvin J, Ali Z, Wang L, Lu L, Williams R W, Rosen G D, Csernansky J G, Cheverud J M
Abstract excerpt
To investigate whether there are separate or shared genetic influences on the development of the thalamus and cerebral cortex, we identified quantitative trait loci (QTLs) for relevant structural volumes in BXD recombinant inbred (RI) strains of mice. In 34 BXD RI strains and two parental strains (C57BL/6J and DBA/2J), we measured the volumes of the entire thalamus and cortex gray matter using point counting and...
Topics
- Animals
- Behavior, Animal
- Cerebral Cortex
- Chromosome Mapping
- Chromosomes
- Gene Expression
- Mice
- Mice, Mutant Strains
- Organ Size
- Phenotype
- Quantitative Trait Loci