Article
Increased frequency of the 2437T allele of the heat shock protein 70-Hom gene in an aged Irish population.
Experimental gerontology - 1 May 2003
Ross Owen A, Curran Martin D, Crum Karen A, Rea I Maeve, Barnett Yvonne A, Middleton Derek
Abstract excerpt
The frequency of the functional polymorphism, T2437C transversion (Met-->Thr), in the HSP 70-Hom gene was investigated within a healthy aged Irish population using oligonucleotide probes. The 2437T polymorphic nucleotide was observed to increase in the elderly, although not attaining statistical significance. The TT genotype was observed to be significantly increased within the Irish aged population (p=0.03),...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
