Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced heat shock response in human mononuclear cells during aging and its association with polymorphisms in HSP70 genes.

Cell stress & chaperones - 1 Jan 2006

Singh Ripudaman, Kølvraa Steen, Bross Peter, Jensen Uffe Birk, Gregersen Niels, Tan Qihua, Knudsen Christian, Rattan Suresh I S

Abstract excerpt

Age-dependent changes in heat shock response (HSR) were studied in mononuclear cells (monocytes and lymphocytes) collected from young (mean age = 22.6 +/- 1.7 years) and middle-aged (mean age = 56.3 +/- 4.7 years) subjects after 1 hour of heat shock at 42 degrees C. Genotype-specific HSR was measured by genotyping the subjects for 3 single nucleotide polymorphisms, HSPA1A(A-110C), HSPA1B(A1267G), and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Cells, Cultured

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heat-Shock Response

Share to HSP70 Heat-Shock Proteins

Share to Leukocytes, Mononuclear

Share to Lymphocytes

Share to Polymorphism, Genetic

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 17009593
DOI: 10.1379/csc-184r.1
PMCID: PMC1576475

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced heat shock response in human mononuclear cells during aging and its association with polymorphisms in HSP70 genes.PMID 17009593Read ↗

Anti-inflammatory heat shock protein 70 genes are positively associated with human survival.Semantic proximity Read ↗

Heat-shock protein 70 genes and human longevity: a view from Denmark.Semantic proximity Read ↗

Role of heat shock proteins in aging and chronic inflammatory diseasesSemantic proximity Read ↗

The association of heat shock protein genetic polymorphisms with age-related hearing impairment in Taiwan.Semantic proximity Read ↗

Association of heat shock proteins with all-cause mortality.Semantic proximity Read ↗

A Model of Exposure to Extreme Environmental Heat Uncovers the Human Transcriptome to Heat StressSemantic proximity Read ↗

Genetic determinants of HSP70 gene expression following heat shock.Semantic proximity Read ↗

Genetics of human longevity with emphasis on the relevance of HSP70 as candidate genesSemantic proximity Read ↗

Cellular thermotolerance is associated with heat shock protein 70.1 genetic polymorphisms in Holstein lactating cows.Semantic proximity Read ↗

Age-related attenuation in the expression of the major heat shock proteins in human peripheral lymphocytesSemantic proximity Read ↗

Serum heat shock protein 70 level as a biomarker of exceptional longevity.Semantic proximity Read ↗

Genetic variations of HSPA1A, the heat shock protein levels, and risk of atherosclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.