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Article

Biochemical basis of the constitutive coprotease activity of RecA P67W protein.

Biochemistry - 20 May 2003

Mirshad Julie K, Kowalczykowski Stephen C

Abstract excerpt

The mutation of Pro67 to Trp (P67W) in the Escherichia coli RecA protein results in reduced recombination and constitutive coprotease phenotypes. We examined the biochemical properties of this mutant in an effort to understand these altered behaviors. We find that RecA P67W protein can access single-stranded DNA (ssDNA) binding sites within regions of secondary structure more effectively than wild-type protein,...

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Source

Identifiers

PMID: 12741852
DOI: 10.1021/bi027232q

Genes

SSB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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