Article
Genetic alterations responsible for metastatic phenotypes of lung cancer cells.
Clinical & experimental metastasis - 1 Jan 2003
Yokota Jun, Nishioka Michiho, Tani Masachika, Kohno Takashi
Abstract excerpt
It is now widely accepted that human carcinogenesis is a multi-step process and phenotypic changes during cancer progression reflect the sequential accumulation of genetic alterations in cells. Thus, in order to understand the process of acquisition of metastatic phenotypes in cancer cells, it is indispensable to identify genes whose alterations accumulate during cancer progression and correlate with metastatic...
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