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Article

RB18A enhances expression of mutant p53 protein in human cells.

FEBS letters - 25 Apr 2005

Lottin-Divoux Séverine, Barel Monique, Frade Raymond

Abstract excerpt

RB18A (TRAP220/DRIP205) is a cofactor of transcription. We herein demonstrated that RB18A downregulated p53 and upregulated MDM2 promoters. These RB18A regulations, not modified by p53wt expression, were inhibited by mutant p53 (p53mut) expression, which directly interacts with RB18A D5 domain. I...

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Source

Identifiers

PMID: 15848166
DOI: 10.1016/j.febslet.2005.03.026

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15848166-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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