Article
Spirometric and gas transfer discordance in a α1 -antitrypsin deficiency. patient characteristics and progression.
Chest - 1 Jun 2014
Ward Helen, Turner Alice M, Stockley Robert A
Abstract excerpt
BACKGROUND: Phenotypic differences in physiologic, radiologic, and clinical characteristics are increasingly recognized in COPD. The factors associated with a 1 -antitrypsin deficiency (A1AD)physiologic phenotypes and how they progress with time have yet to be explained. METHODS: The study comprised 530 patients with the homozygote Z variant (PiZZ) A1AD; 255 patients had greater than or equal to 3 years of data...
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