Article
Long-term evolution of lung function in individuals with alpha-1 antitrypsin deficiency from the Spanish registry (REDAAT).
International journal of chronic obstructive pulmonary disease - 1 Jan 2018
Esquinas Cristina, Serreri Sonia, Barrecheguren Miriam, Rodriguez Esther, Nuñez Alexa, Casas-Maldonado Francisco, Blanco Ignacio, Pirina Pietro, Lara Beatriz, Miravitlles Marc
Abstract excerpt
Background: The clinical course of alpha-1 antitrypsin deficiency (AATD) is very heterogeneous. It is estimated that 60% of individuals with severe AATD (Pi*ZZ) develop emphysema. The main objective of this study was to describe the outcomes of long-term lung function in individuals with AATD-associated emphysema after at least 8 years of follow-up. Materials and methods: We performed a retrospective analysis of...
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