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Article

Detection of H-2 alleles by PCR-RFLP-an alternative to flow cytometry in the screening of transgenic mice.

Journal of immunological methods - 1 May 2003

Klebs Sven H G, Hoffmann Matthias W, Musholt Petra B, Bayer Bettina, Musholt Thomas J

Abstract excerpt

An increasing number of experimental models is based on well-defined transgenic mice in medical and biological research. Particularly in settings in which transgenic recombinants are used, a fast and reliable method is needed to screen for a defined H-2 background. For this purpose, flow cytometry with specific monoclonal antibodies is the standard procedure. However, epitopes of closely related rodent strains...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12738373
DOI: 10.1016/s0022-1759(03)00063-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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