Article
Analysis of TP53 and PTEN in gliomatosis cerebri.
Acta neuropathologica - 1 Jun 2003
Mawrin Christian, Kirches Elmar, Schneider-Stock Regine, Scherlach Cordula, Vorwerk Christian, Von Deimling Andreas, Van Landeghem Frank, Meyermann Richard, Bornemann Antje, Müller Andreas, Romeike Bernd, Stoltenburg-Didinger Gisela, Wickboldt Jürgen, Pilz Peter, Dietzmann Knut
Abstract excerpt
Gliomatosis cerebri (GC) is a rare glial neoplasm with extensive diffuse brain infiltration but relative preservation of the underlying architecture. Previous molecular studies, mostly analyzing biopsy samples, have suggested an astrocytic origin of GC, but a larger collective of autopsy tissue has not been investigated so far. Furthermore, whether the widespread neoplastic infiltration is based on a monoclonal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.