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Article

Lewis enzyme (alpha1-3/4 fucosyltransferase) polymorphisms do not explain the Lewis phenotype in the gastric mucosa of a Portuguese population.

Journal of human genetics - 1 Jan 2003

Serpa Jacinta, Almeida Raquel, Oliveira Carla, Silva Filipe Santos, Silva Elisabete, Reis Celso, Le Pendu Jacques, Oliveira Graça, Ribeiro Luís Manuel Cunha, David Leonor

Abstract excerpt

The human alpha-1,3/4 fucosyltransferase III (FucT III) catalyses the synthesis of Lewis antigens including Le(b) antigen which is a ligand for Helicobacter pylori adhesion. Several polymorphisms have been described in the FUT3 gene affecting both the transmembrane and catalytic domains, some of which affect the enzyme activity. The aim of the present work was to study the Lewis gene polymorphisms in a Caucasian...

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Source

Identifiers

PMID: 12730721
DOI: 10.1007/s10038-003-0007-5

Genes

FUT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lewis enzyme (alpha1-3/4 fucosyltransferase) polymorphisms do not explain the Lewis phenotype in the gastric mucosa of a Portuguese population.PMID 12730721Read ↗

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