Article
Identification of rocA, a positive regulator of covR expression in the group A streptococcus.
Journal of bacteriology - 1 May 2003
Biswas Indranil, Scott June R
Abstract excerpt
In the group A streptococcus (GAS; Streptococcus pyogenes), a two-component system known as CovRS (or CsrRS) regulates about 15% of the genes, including several important virulence factors like the hyaluronic acid capsule. Most of these genes, including covR itself, are negatively regulated by CovR. We have isolated two independent ISS1 insertions in an open reading frame (ORF) that increases CovR expression as...
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