Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RocA Is an Accessory Protein to the Virulence-Regulating CovRS Two-Component System in Group A Streptococcus

15 Aug 2017

Abstract excerpt

ABSTRACT Regulating gene expression during infection is critical to the ability of pathogens to circumvent the immune response and cause disease. This is true for the group A Streptococcus (GAS), a pathogen that causes both invasive (e.g., necrotizing fasciitis) and noninvasive (e.g., pharyngitis) diseases. The c ontrol o f v irulence (CovRS) two-component system has a major role in regulating GAS virulence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacterial Identification and Susceptibility Testing
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28808155
DOI: 10.1128/iai.00274-17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RocA Is an Accessory Protein to the Virulence-Regulating CovRS Two-Component System in Group A StreptococcusPMID 28808155Read ↗

The group A Streptococcus accessory protein RocA: regulatory activity, interacting partners and influence on disease potentialSemantic proximity Read ↗

Single Amino Acid Replacements in RocA Disrupt Protein-Protein Interactions To Alter the Molecular Pathogenesis of Group A Streptococcus.Semantic proximity Read ↗

The two faces of Janus: virulence gene regulation by CovR/S in group A streptococciSemantic proximity Read ↗

RocA Truncation Underpins Hyper-Encapsulation, Carriage Longevity and Transmissibility of Serotype M18 Group A StreptococciSemantic proximity Read ↗

Regulatory rewiring confers serotype-specific hyper-virulence in the human pathogen group A Streptococcus.Semantic proximity Read ↗

Identification of rocA, a positive regulator of covR expression in the group A streptococcus.Semantic proximity Read ↗

RivR Is a Negative Regulator of Virulence Factor Expression in Group A StreptococcusSemantic proximity Read ↗

Contribution of a genomic accessory region encoding a putative cellobiose phosphotransferase system to virulence of Streptococcus pneumoniae.Semantic proximity Read ↗

Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling.Semantic proximity Read ↗

Molecular Targets in Streptococcus pyogenes for the Development of Anti-Virulence AgentsSemantic proximity Read ↗

The CovR regulatory network drives the evolution of Group B Streptococcus virulenceSemantic proximity Read ↗

Intergenic Variable-Number Tandem-Repeat Polymorphism Upstream of rocA Alters Toxin Production and Enhances Virulence in Streptococcus pyogenes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.