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Article

Structural and functional defects caused by point mutations in the alpha-crystallin domain of a bacterial alpha-heat shock protein.

Journal of molecular biology - 9 May 2003

Lentze Nicolas, Studer Sonja, Narberhaus Franz

Abstract excerpt

The diverse family of alpha-crystallin-type small heat shock proteins (alpha-Hsps or sHsps) is characterised by a central, moderately conserved alpha-crystallin domain. Oligomerisation followed by dissociation of subparticles is thought to be a prerequisite for chaperone function. We demonstrate that HspH, a bacterial alpha-Hsp from the soybean-symbiont Bradyrhizobium japonicum, assembles into dynamic complexes...

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Identifiers

PMID: 12729765
DOI: 10.1016/s0022-2836(03)00356-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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