Article
Interleukin-2 gene polymorphism is associated with renal but not cardiac transplant outcome.
Transplantation proceedings - 1 Jun 2003
Morgun A, Shulzhenko N, Rampim G F, Medina J O P, Machado P G P, Diniz R V Z, Almeida D R, Gerbase-DeLima M
Abstract excerpt
It was recently shown that IL-2 gene single nucleotide polymorphism (SNP) at position -330 (G-->T) is related to in vitro cytokine production levels, with the T/T and T/G genotypes being associated with low production and the G/G genotype associated with high production. The objective of this study was to investigate a possible influence of this polymorphism on renal and cardiac allograft outcomes. IL-2 SNP G-T...
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