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Article

Genetic polymorphisms in IL-2, IL-10, TGF-β1, and IL-2RB and acute rejection in renal transplant patients.

Clinical transplantation - 1 Jun 2014

Chen Zhigang, Bouamar Rachida, Van Schaik Ron H N, De Fijter Johan W, Hartmann Anders, Zeier Martin, Budde Klemens, Kuypers Dirk R J, Weimar Willem, Hesselink Dennis A, Van Gelder Teun

Abstract excerpt

Acute rejection (AR) remains a concern for kidney transplantation. Cytokines are key mediators in the induction and effector phases of all immune and inflammatory responses. Single nucleotide polymorphisms (SNPs) in cytokines and their receptors may relate to AR. We investigated the relation between AR and SNPs in the genes encoding for IL-2(-330G>T), IL-10(-592C>A and -1082G>A), TGF-β1(915G>C), and...

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Identifiers

PMID: 24579958
DOI: 10.1111/ctr.12346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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