Article
Analysis of cytokine gene polymorphisms in recipient's matched with living donors on acute rejection after renal transplantation.
Molecular and cellular biochemistry - 1 Apr 2008
Manchanda Parmeet Kaur, Mittal Rama Devi
Abstract excerpt
Despite advances in immunosuppressive therapy in last few years, allograft rejection still remains the concern for kidney graft failure. Cytokines are key mediators in the induction and effector phases of all immune and inflammatory responses. They are not allospecific so both recipient as well as donor cells may be subjected to cytokine changes. We sought to ascertain whether IL-1B -511, IL-1B +3954, TNF-A -308,...
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