Article
NAT2 slow acetylator function as a risk indicator for age-related cataract formation.
Pharmacogenetics - 1 May 2003
Meyer David, Parkin Donald P, Seifart Heine I, Maritz J Stefan, Engelbrecht Albertus H, Werely Cedric J, van Helden Paul D
Abstract excerpt
OBJECTIVES: To show that the slow arylamine N-acetyltransferase type 2 (NAT2) catalysed acetylator function is associated with the development of age-related cataracts. METHODS: Both the acetylator phenotype and genotype of 139 patients with age-related cataracts were determined, and the distribution of the acetylator subtypes in the case population was compared with the distribution in the general (control)...
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