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Identification and Characterization of Three New Components of the mSin3A Corepressor Complex

30 Apr 2003

Abstract excerpt

The mSin3A corepressor complex contains 7 to 10 tightly associated polypeptides and is utilized by many transcriptional repressors. Much of the corepressor function of mSin3A derives from associations with the histone deacetylases HDAC1 and HDAC2; however, the contributions of the other mSin3A-associated polypeptides remain largely unknown. We have purified an mSin3A complex from K562 erythroleukemia cells and...

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PMID: 12724404
DOI: 10.1128/mcb.23.10.3456-3467.2003

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